My name is Emmanuel, and I am a lecturer in Nigeria who is interested in how climate change is making fungi in the environment to be fit to cause diseases. The case of Candida auris is one, C. auris is the first known pathogen that has emerged as a result of climate change and phage therapy as a means of combating antibiotic resistance.
I've been unsuccessful with open philanthropy grants and EA funds, possibly because I don't understand what they actually fund or how to format my application to meet their requirements. In Nigeria, I recently established a phage bank with the goal of developing phage therapy-ready products that can be used to treat specific bacterial infections. A recent study has shown that western sub-Saharan Africa, has the highest all-age death rate attributable to resistance at 27·3 deaths per 100 000. We are beginning to see untreatable pathogens.
My first thought was that this is a good fit for the cause advocated by Open Philanthropy, but with few rejections. I'm having second thoughts. I'm proposing a lab that will produce phage-ready products for clinicians and will also develop low-cost phage-based solutions for treating water against Typhoid fevers and cleaning hospital environments. I'm wondering how to structure this so that it aligns with the goals of Effective altruism.
I require guidance. I'd like to speak with someone who is familiar with the process to get a head start, or can I obtain a sample of a successful proposal to use as a guide in the future? Who would be willing to review my proposal and offer suggestions for meeting EA objectives and making a maximum impact?
Thanks for your comment. Yes! The recent disability-adjusted life-years projection for drug resistance just released showed a total of 4·95 million deaths associated with bacterial AMR in 2019, including 1·27 million deaths attributable to bacterial AMR. At the regional level, we estimated the all-age death rate attributable to resistance to be highest in western sub-Saharan Africa, at 27·3 deaths per 100 000 . Six pathogens contributed to the largest burden of AMR in 2019 (E coli, S aureus, K pneumoniae, S pneumoniae, A baumannii,... (read more)